Module title: Biochemistry

SCQF level: 08:
SCQF credit value: 20.00
ECTS credit value: 10

Module code: BMS08101
Module leader: Samantha Campbell Casey
School School of Applied Sciences
Subject area group: Biomedical Science
Prerequisites

A knowledge of cell biology, biological chemistry

2018/9, Trimester 1, Face-to-Face, Edinburgh Napier University
Occurrence: 002
Primary mode of delivery: Face-to-Face
Location of delivery: SIGHTHILL
Partner: Edinburgh Napier University
Member of staff responsible for delivering module: Samantha Campbell Casey
Module Organiser:


Learning, Teaching and Assessment (LTA) Approach:
A mixture of face to face and independent learning will be used to support students on this module. Face to face teaching will involve lectures, tutorials and practical classes where the principles of biochemistry will be taught. Lectures cover learning outcomes 1-5 and explain core concepts of the module, and practicals will focus on learning outcomes 1, 2 and 6. To ensure that every learner is as active as possible all classes will contain collaborative, interactive exercises and suggestions for further study. Questions are encouraged within all face-to-face teaching, and via Moodle.

Formative Assessment:
This is a core module which is a building block for all the biological degrees therefore it is essential that students are able to demonstrate knowledge and understanding in all areas of the subject. As such there are a number of self-assessment tests and online support materials to help students with the content of the module within Moodle to allow students to gain a measure of their performance on the module. Self-assessment tests will be made available throughout the module to support the module content and as such these will occur weekly. These self-assessment tests will provide students with feedback on their understanding of the module content. Students will have the opportunity to take these assessments more than once to help to close the feedback cycle. These formative self-assessment tests will provide practice opportunities in advance of the digital examination that will take place in week 12. Formative feedforward sessions for the lab report will take place in weeks 5,6 and 7 and will provide students with an opportunity to engage with the criteria for assessment and to get feedback on a small section of the report.



Summative Assessment:
There are two components of assessment on this module, a laboratory report due in week 10, worth 50% of the module mark, and a digital examination due in week 12 also worth 50% of the module mark.

The laboratory report, learning outcomes 1, 2 and 6, will require students to undertake statistical analysis of data obtained during the practical classes, to prepare appropriate graphs and/or tables and write a scientific report which will include a reflection on the value of the experiments, suggestions for improvement and also to put this in an appropriate context.

The digital examination will take place in week 12 and will consist of a pool of 50 randomised questions covering learning outcomes 3-5 on the module. Students will have a time limit of 1 hour to complete this digital test.


Student Activity (Notional Equivalent Study Hours (NESH))
Mode of activityLearning & Teaching ActivityNESH (Study Hours)
Face To Face Lecture 20
Face To Face Tutorial 6
Face To Face Practical classes and workshops 12
Independent Learning Guided independent study 162
Total Study Hours200
Expected Total Study Hours for Module200


Assessment
Type of Assessment Weighting % LOs covered Week due Length in Hours/Words
Laboratory report 50 1,2 & 6 10 HOURS= 0, WORDS= 1200
Digital Examination (not Centrally Timetabled) 50 3,4 & 5 12 HOURS= 1, WORDS= 0
Component 1 subtotal: 50
Component 2 subtotal: 50
Module subtotal: 100

Description of module content:

This module will expand your basic knowledge of biochemistry by introducing you to the principles of metabolism (catabolism and anabolism) and the manner in which metabolic pathways are integrated and regulated. These biochemical principles are universal and a range of different examples including plant, bacteria and animal will be used to support the teaching. The role of the protein structure/function relationship will be a key focus of the module and will underpin all aspects, but specifically in enzymology and kinetics and how this can then be applied in the real world for development of new inhibitors to be used in a therapeutic or beneficial way. We will look at catabolism and anabolism of key molecules including carbohydrates, proteins and lipids, how these pathways are regulated and integrate together and how cellular metabolism adapts to changing conditions such as feeding, fasting and also disease states. There will also be an opportunity in the module undertake analysis and measurements of biochemical parameters and test some of the key principles of biochemistry within the laboratory.

Learning Outcomes for module:

Upon completion of this module you will be able to
LO1: Discuss the importance of the protein structure/function relationship using a range of different examples.
LO2: Describe the properties and specificity of enzymes and use a problem solving approach to determine enzyme kinetic data.
LO3: Explain how catabolic and biosynthetic pathways are integrated within metabolism and the major advantages this brings to the organism.
LO4: Explain the mechanisms by which metabolic pathways are regulated both generally and specifically.
LO5: Describe the consequences of disturbances in metabolism using a range of suitable examples.
LO6: Understand how to investigate and measure biochemical parameters within the laboratory using a range of techniques.

Indicative References and Reading List - URL:

Recommended - CAMPBELL, M.K. AND FARRELL S.O (2015) BIOCHEMISTRY: CENGAGE LEARNING, 8th ed. - ISBN: 9781285429106
Recommended - BENDER, D (2014) INTRODUCTION TO NUTRITION AND METABOLISM: CRC PRESS, 5th ed. - ISBN: 9781466572249
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