A knowledge of cell biology, biological chemistry

This module will expand your basic knowledge of biochemistry by introducing you to the
principles of metabolism (catabolism and anabolism) and the manner in which
metabolic pathways are integrated and regulated. These biochemical principles are
universal and a range of different examples including plant, bacteria and animal will be
used to support the teaching. The role of the protein structure/function relationship will be
a key focus of the module and will underpin all aspects, but specifically in enzymology
and kinetics and how this can then be applied in the real world for development of new
inhibitors to be used in a therapeutic or beneficial way. We will look at catabolism and
anabolism of key molecules including carbohydrates, proteins and lipids, how these
pathways are regulated and integrate together and how cellular metabolism adapts to
changing conditions such as feeding, fasting and also disease states. There will also be
an opportunity in the module undertake analysis and measurements of biochemical
parameters and test some of the key principles of biochemistry within the laboratory

Upon completion of this module you will be able to
LO1: Discuss the importance of the protein structure/function relationship using a range
of different examples.
LO2: Describe the properties and specificity of enzymes and use a problem solving
approach to determine enzyme kinetic data.
LO3: Explain how catabolic and biosynthetic pathways are integrated within metabolism
and the major advantages this brings to the organism.
LO4: Explain the mechanisms by which metabolic pathways are regulated both generally
and specifically.
LO5: Describe the consequences of disturbances in metabolism using a range of
suitable examples.
LO6: Understand how to investigate and measure biochemical parameters within the
laboratory using a range of techniques.