Module title: Pharmacology and Pathobiology

SCQF level: 09:
SCQF credit value: 20.00
ECTS credit value: 10

Module code: BMS09111
Module leader: Sharron Vass
School School of Applied Sciences
Subject area group: Biomedical Science
Prerequisites

Examples of Equivalent Learning Level 8 (2nd year University level) Physiology, Biochemistry

2019/0, Trimester 2, FACE-TO-FACE,
Occurrence: 001
Primary mode of delivery: FACE-TO-FACE
Location of delivery: SIGHTHILL
Partner:
Member of staff responsible for delivering module: Sharron Vass
Module Organiser:


Learning, Teaching and Assessment (LTA) Approach:
This module will be taught using a combination of interactive lectures, tutorials, practical classes and independent computer workshops. Lectures will cover the essentials of the main topics and tutorials will facilitate discussion and a deeper understanding of particular mechanisms.

An assessed element of this module will include the production of a scientific website. The work will be performed in teams, and substantial time will be given to computer lab sessions to allow interaction, literature searching and production of the web-site. The web-site design will incorporate an element of peer assessment.

Moodle support will be available to provide a repository for lecture materials and learning resources.


Formative Assessment:
The formative assessment element of this module will be developing a protocol to test the efficacy of medications. You will be given a selection of reagents and equipment, then using the practical skills you have developed to date, working in pairs, you will determine the best method to compare and contrast two different types of medication. Oral formative feedback will be given on your protocol design and your practical technique.

Summative Assessment:
There will be two elements of summative assessment for this module including; designing a scientific website and a 3 hour formal exam.

For week 12 you will design and create a scientific website based on a particular disease, it will focus on the mode of diagnosis and current therapeutic options. The disease will be chosen by your team from a pre-determined list. You will be asked to provide feedback to your peers using pre-determined criteria. This task specifically covers LOs 3 & 4.

The final exam will take place at the end of the module. This exam will cover elements from the lectures, tutorials and practical sessions and will incorporate LOs 1-4.



Student Activity (Notional Equivalent Study Hours (NESH))
Mode of activityLearning & Teaching ActivityNESH (Study Hours)
Independent Learning Groupwork (Independent Study) 25
Face To Face Centrally Time Tabled Examination 3
Independent Learning Guided independent study 140
Face To Face Lecture 22
Face To Face Tutorial 4
Face To Face Practical classes and workshops 6
Total Study Hours200
Expected Total Study Hours for Module200


Assessment
Type of Assessment Weighting % LOs covered Week due Length in Hours/Words
Centrally Time Tabled Examination 60 1,2, 3 & 4 14/15 HOURS= 3
Project - Written 40 3 & 4 12 HOURS= 0, WORDS= 1500
Component 1 subtotal: 60
Component 2 subtotal: 40
Module subtotal: 100

Description of module content:

This module will build upon the concepts and understanding gained in your 1st and 2nd year physiology, genetics, and biochemistry modules, and will integrate with other 3rd year biomedical sciences modules, to develop a deeper understanding of disease mechanisms and how they may be treated.
The module includes an introduction to the general principles of pharmacology, and will focus on how therapeutic drugs are administered, absorbed, distributed, metabolised and excreted by the body. Targets for therapeutic drugs will be examined, including receptor theory and dose response relationships, and the importance of drug specificity.
Pathobiology is the study of how the disease arises in the first place, i.e. the disease mechanism. The pathobiology of any disease can normally be traced back to one of four main factors; genetic, environmental, pathogenic or life-style choices. Through examination of specific examples of disease you will develop a detailed knowledge of the principal causes of those diseases, and how they may be treated.
The practical elements of this module will include performing a cell-based toxicity assay, and developing a protocol to compare the effectiveness of over-the-counter medications.
There will also be a teamwork task, where you will be asked to produce a scientific website designed to give patients and health care practitioners information on the pathology of a particular disease and the molecular mechanisms of current treatment options.
Throughout the module, you will be expected to engage with primary research literature.

Learning Outcomes for module:

LO1: Illustrate the molecular aspects of how drugs act: receptor classification and drug-receptor interactions; dose-response relationships; differentiate between agonists and antagonists
LO2: Examine the relationship between absorption, distribution, metabolism, and excretion of drugs and xenobiotics.
LO3: Critically appraise current therapeutics used to treat and alleviate disease.
LO4: Utilise specialised information sources and evaluate primary literature and apply this knowledge using specific disease examples.

Indicative References and Reading List - URL:

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