Core Module Information
Module title: Pharmaceutics: macromolecules

SCQF level: 09:
SCQF credit value: 20.00
ECTS credit value: 10

Module code: BMS09114
Module leader: Fiona Kerr
School School of Applied Sciences
Subject area group: LIFE SCIENCES
Prerequisites

N/A

Description of module content:

This module enhances your understanding of the structure and function of key macromolecules, including the biological relevance and their role in the development of new therapeutics. You will learn about the role of proteins, peptides, carbohydrates, nucleotides and lipids. You will be exposed to the basic chemistry and reactivity of the main “building blocks” of macromolecules and this will build on your learning from the small molecules module. The structure of these macromolecules with regards to their clinical implications, interaction with biological targets and stability will be discussed. You will also learn about their role in disease and treatment.
You will be provided with the skills for graphically representing these molecules using software routinely employed in drug discovery research during tutorials, demonstrations, and activities in PC labs. Tools for predicting secondary structure of the main macromolecules will be presented and demonstrated.
You will get hands on experience in the lab with activities specifically designed to explore the different types of molecules to investigate their properties and function.

Learning Outcomes for module:

LO1: understand the structure and biological function of the key macromolecules and their role in the development of new therapeutics.
LO2: identify the main organic building blocks by exploiting the reactivity of their functional group and develop an understanding of the chemistry of the macromolecules.
LO3: rationally appraise the therapeutic capabilities and limitations of biopharmaceuticals.
LO4: demonstrate awareness of the processes happening from the isolation of the biopharmaceutic API to its release on the market

Full Details of Teaching and Assessment
2022/3, Trimester 1, FACE-TO-FACE,
VIEW FULL DETAILS
Occurrence: 001
Primary mode of delivery: FACE-TO-FACE
Location of delivery: SIGHTHILL
Partner:
Member of staff responsible for delivering module: Samantha Campbell Casey
Module Organiser:


Learning, Teaching and Assessment (LTA) Approach:
Theoretical elements of the module will be taught via lectures and tutorials and supported by
additional materials on Moodle to aid your understanding and progression through the
module. Skills for graphically representing molecules by software routinely employed in
drug discovery research will be taught in practicals, via demonstration, and activities in
PC labs. Practical laboratory sessions will involve activities specifically designed to stimulate your interest and curiosity for the classes of compounds being covered and will require use of GLP practice and the keeping of an appropriately GLP compliant lab book.
Assessments will include a lab report based on practical classes and use of software for
analysis of data collected (LOs 1-3); and a group presentation based on a macromolecule of your choice (e.g. including information about how it can be used as a biopharmaceutical, future prospects, challenges and how it compares to small molecules etc) (LOs 2-4). A series of class presentations on alternative topics during tutorial sessions will give you an opportunity to practice speaking and also receive feedback in advance of the final assessed presentation.


Formative Assessment:
Formative feedback will be provided during practical sessions to inform your summative
lab report. A formative tutorial will also be provided to support you with this component of
assessment.
Class presentations and interactive poster development will be used during tutorial
sessions to provide formative feedback for your summative group presentation and will give you an opportunity to practice speaking and help build your confidence.


Summative Assessment:
Assessments will be a lab report based on practical classes and use of software for analysis of data collected (LOs 1-3); and a group presentation based on a macromolecule (about how it can be used as a biopharmaceutical) (LOs 2-4)

Student Activity (Notional Equivalent Study Hours (NESH))
Mode of activityLearning & Teaching ActivityNESH (Study Hours)
Face To Face Lecture 24
Face To Face Tutorial 12
Face To Face Practical classes and workshops 12
Independent Learning Guided independent study 152
Total Study Hours200
Expected Total Study Hours for Module200


Assessment
Type of Assessment Weighting % LOs covered Week due Length in Hours/Words
Laboratory report 40 1-3 8 , WORDS= 1000
Oral Presentation 60 2-4 13 HOURS= 00.15
Component 1 subtotal: 40
Component 2 subtotal: 60
Module subtotal: 100
2022/3, Trimester 1, FACE-TO-FACE, Edinburgh Napier University
VIEW FULL DETAILS
Occurrence: 002
Primary mode of delivery: FACE-TO-FACE
Location of delivery: SIGHTHILL
Partner: Edinburgh Napier University
Member of staff responsible for delivering module: Samantha Campbell Casey
Module Organiser:


Learning, Teaching and Assessment (LTA) Approach:
Theoretical elements of the module will be taught via lectures and supported by additional materials on Moodle to aid your understanding and progression through the module. Skills for graphically representing molecules by software routinely employed in drug discovery research will be taught in practicals, via demonstration, and activities in PC labs. In tutorials, emphasis will also be placed on the main techniques applied to formulate and quality control biologics, with the aim of improving their performance and/or mitigate their instability, using a problem-solving approach. Practical laboratory sessions will involve activities specifically designed to stimulate your interest and curiosity for the classes of compounds being covered and will require use of GLP practice and the keeping of an appropriately GLP compliant lab book.

Assessments will include a lab report based on practical classes and use of software for analysis of data collected (LOs 1-3); and an individual presentation based on a macromolecule of your choice (e.g. including information about production, quality control, challenges etc) (LOs 2-4)




Formative Assessment:
Formative feedback will be provided during practical sessions to inform your summative lab report. A formative tutorial will also be provided to support you with this component of assessment.
Group presentations and interactive poster development will be used during tutorial sessions to provide formative feedback for your summative individual presentation.


Summative Assessment:
Assessments will be a lab report based on practical classes and use of software for analysis of data collected (LOs 1-3); and an individual presentation based on a macromolecule (production, quality control, challenges etc) (LOs 2-4)

Student Activity (Notional Equivalent Study Hours (NESH))
Mode of activityLearning & Teaching ActivityNESH (Study Hours)
Face To Face Lecture 24
Face To Face Tutorial 12
Face To Face Practical classes and workshops 12
Independent Learning Guided independent study 152
Total Study Hours200
Expected Total Study Hours for Module200


Assessment
Type of Assessment Weighting % LOs covered Week due Length in Hours/Words
Laboratory report 40 1-3 8 , WORDS= 1000
Oral Presentation 60 2-4 13 HOURS= 00.15
Component 1 subtotal: 40
Component 2 subtotal: 60
Module subtotal: 100

Indicative References and Reading List - URL:
Contact your module leader