Module title: Introductory & Applied Molecular Genetics (Hong Kong)

SCQF level: 09:
SCQF credit value: 20.00
ECTS credit value: 10

Module code: BMS09601
Module leader: Arthur Robinson
School School of Applied Sciences
Subject area group: Biomedical Science
Prerequisites

There are no pre-requisites for this module to be added

2018/9, Trimester 1, Blended,
Occurrence: 001
Primary mode of delivery: Blended
Location of delivery: HONG KONG
Partner:
Member of staff responsible for delivering module: Arthur Robinson
Module Organiser:


Learning, Teaching and Assessment (LTA) Approach:
Learning & teaching methods including their alignment to LOs
Introductory lecture and tutorial sessions and the supplied study guide cover LOs 1 - 4, while LO5 is covered by laboratory work, for which guidance is given and marking criteria are advised. LOs 1 - 4 is supported by tutorials with local tutors. Questioning is encouraged during face-to-face teaching in tutorials, on-line using Moodle discussion forums, and in laboratory classes. Personalised feedback is given during tutorials and for the laboratory report.



Formative Assessment:
Formative assessment occurs during tutorial sessions when students have the opportunity to discuss and compare their solutions/data with those of others, and with model answers provided by the module leader for the local tutor.

Feedback on the laboratory report is given in stages so that students have an opportunity to improve their performance in subsequent reports in other modules.


Summative Assessment:
Summative assessment takes the form of a laboratory report, and problem solving during Moodle tests (LOs 1 - 4), and a formal examination (LOs 1 - 4).

Student Activity (Notional Equivalent Study Hours (NESH))
Mode of activityLearning & Teaching ActivityNESH (Study Hours)
Face To Face Lecture 12
Face To Face Tutorial 6
Face To Face Practical classes and workshops 12
Independent Learning Guided independent study 167
Face To Face Centrally Time Tabled Examination 3
Total Study Hours200
Expected Total Study Hours for Module200


Assessment
Type of Assessment Weighting % LOs covered Week due Length in Hours/Words
Digital Examination (not Centrally Timetabled) 30 1,2,3,4 2 HOURS= 0, WORDS= 0
Practical Skills Assessment 20 5 9 HOURS= 0, WORDS= 800
Centrally Time Tabled Examination 50 1,2,3,4 14/15 HOURS= 3, WORDS= 0
Component 1 subtotal: 50
Component 2 subtotal: 50
Module subtotal: 100

Description of module content:

Revision of structure, and function of DNA and RNA, and of the genetic code. Induction and genotypic classification of mutations, and their consequences (phenotypic effects). DNA repair (direct, excision, mismatch correction, recombination and "error-prone"). Genetic recombination, bacterial conjugation, and role of the F plasmid in gene transfer. Mapping of chromosomal markers by interrupted mating. Transformation. Transduction. Restriction enzymes and restriction mapping. Cloning DNA sequences using plasmid and bacteriophage vectors. Developments in vector technology. cDNA cloning. Identification of specific clones of interest. Analysis/manipulation of DNA sequences by: polymerase chain reaction (PCR), DNA sequencing, site-directed mutagenesis, and Southern blotting. Regulation of gene expression in prokaryotic and eukaryotic organisms.

Learning Outcomes for module:

LO1: Compare and contrast mechanisms of mutation, DNA repair, and DNA transfer in Escherichia coli, and derive genetic maps from gene transfer data.
LO2: Determine the genetic and molecular basis of restriction/modification systems and derive restriction maps by interpreting both theoretical and laboratory data.
LO3: Interpret the laboratory principles of gene cloning: the identification, selection and amplification of specific DNA sequences, and the generation of genomic libraries.
LO4: Evaluate the techniques of gene expression analysis and gene function.
LO5: Carry out laboratory transfers, manipulations and analyses of DNA.
LO6: Analyse and interpret subject-specific scientific papers.

Indicative References and Reading List - URL:

Core - HARTL, DL (2014) ESSENTIAL GENETICS – A GENOMICS PERSPECTIVE: JONES AND BARTLETT LEARNING, 6th ed. - ISBN: 9781449686888
Core - MCLENNAN, A, BATES, A, TURNAER,P & WHITE, M (2013) BIOS INSTANT NOTES MOLECULAR BIOLOGY: GARLAND SCIENCE, 4th ed. - ISBN: 9780415684163
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