Core Module Information
Module title: Molecular Genetics (Sri Lanka)

SCQF level: 09:
SCQF credit value: 20.00
ECTS credit value: 10

Module code: BMS09803
Module leader: Nicole Payton
School School of Applied Sciences
Subject area group: Life Sciences

There are no pre-requisites for this module to be added

Description of module content:

Revision of structure, and function of DNA and RNA, and of the genetic code. Induction and genotypic classification of mutations, and their consequences (phenotypic effects). DNA repair (direct, excision, mismatch correction, recombination and “error-prone”). Genetic recombination, bacterial conjugation, and role of the F plasmid in gene transfer. Mapping of chromosomal markers by interrupted mating. Transformation. Transduction. Restriction enzymes and restriction mapping. Cloning DNA sequences using plasmid and bacteriophage vectors. Developments in vector technology. cDNA cloning. Identification of specific clones of interest. Analysis/manipulation of DNA sequences by: polymerase chain reaction (PCR), DNA sequencing, site-directed mutagenesis, and Southern blotting. Regulation of gene expression in prokaryotic and eukaryotic organisms.

Learning Outcomes for module:

Upon completion of this module you will be able to
LO1: Compare and contrast mechanisms of mutation, DNA repair, and DNA transfer in Escherichia coli, and derive genetic maps from gene transfer data.
LO2: Determine the genetic and molecular basis of restriction/modification systems and derive restriction maps by interpreting both theoretical and laboratory data.
LO3: Interpret the laboratory principles of gene cloning: the identification, selection and amplification of specific DNA sequences, and the generation of genomic libraries.
LO4: Evaluate the techniques of gene expression analysis and gene function.
LO5: Carry out laboratory transfers, manipulations and analyses of DNA.

Full Details of Teaching and Assessment
2023/4, Trimester 1, FACE-TO-FACE,
Occurrence: 001
Primary mode of delivery: FACE-TO-FACE
Location of delivery: SRI LANKA
Member of staff responsible for delivering module: Nicole Payton
Module Organiser:

Student Activity (Notional Equivalent Study Hours (NESH))
Mode of activityLearning & Teaching ActivityNESH (Study Hours)
Face To Face Lecture 22
Face To Face Tutorial 8
Face To Face Practical classes and workshops 12
Independent Learning Guided independent study 155
Face To Face CL_TST 3
Total Study Hours200
Expected Total Study Hours for Module200

Type of Assessment Weighting % LOs covered Week due Length in Hours/Words
Centrally Time Tabled Examination 30 1-4 2 HOURS= 0, WORDS= 0
Practical Skills Assessment 20 5 9 HOURS= 0, WORDS= 800
Centrally Time Tabled Examination 50 1-4 14/15 HOURS= 3, WORDS= 0
Component 1 subtotal: 50
Component 2 subtotal: 50
Module subtotal: 100

Indicative References and Reading List - URL:
BMS09803 Molecular Genetics SL