Core Module Information
Module title: Analytical methods in drug development

SCQF level: 10:
SCQF credit value: 20.00
ECTS credit value: 10

Module code: BMS10112
Module leader: Giacomo Russo
School School of Applied Sciences
Subject area group: LIFE SCIENCES


Description of module content:

During the study of this module, you will be introduced to the basics of drug analysis and its main applications. You will consider the challenges associated with the preparation of biological samples for pharmaceutical analysis. You will gain understanding of an array of chemical separations, with an emphasis on gas and liquid chromatography, the main analytical techniques currently exploited in drug development.

This will feed into the detection of chemicals and their characterization via spectrometric and spectroscopic techniques, including mass spectrometry, UV – visible spectroscopy, NMR etc. In parallel, you will develop skills in laboratory maths and statistics to determine whether scientific results are robust, allowing meaningful conclusions to be drawn.

You will acquire the skills necessary to establish meaningful connections between the spectral data and the molecular features of chemical of pharmaceutical interest. This will enable you to collate a number of experimental pieces of information and formulate hypothesis on the molecular structures of chemicals of pharmaceutical interest.

Learning Outcomes for module:

LO1: Compare and contrast the main analytical methods that are applied in drug development.

LO2: Evaluate the essential theory and practical applications of separation techniques

LO3: Identify the challenges associated with biological sample preparation for pharmaceutical analysis

LO4: Demonstrate the skills necessary to determine molecular structures from spectral evidence

LO5: Demonstrate appropriate skills in laboratory maths and statistics

Full Details of Teaching and Assessment
2022/3, Trimester 1, FACE-TO-FACE,
Occurrence: 001
Primary mode of delivery: FACE-TO-FACE
Location of delivery: SIGHTHILL
Member of staff responsible for delivering module: Giacomo Russo
Module Organiser:

Learning, Teaching and Assessment (LTA) Approach:
Theoretical elements of the module will be taught using lectures and tutorials supported by suitable additional learning materials on Moodle to aid your understanding and progression through the module. Emphasis will be on the interpretation analytical data and the understanding of the methods used to obtain them. Therefore, there will be a large problem-solving element supported by tutorials to allow for formative development of suitable skills and knowledge. One component of assessment will be a quiz covering separation science, statistics and techniques for chemical identification (LO1, 2, 3, 5) and the other assessment will be a spectral/ chromatography evidence-based report (LOs 2, 4).

Formative Assessment:
The experimental data interpretation tutorial sessions will address practical aspects of theory, which will support formative learning. This will feed into the spectral/ chromatography evidence-based report of your assessment. The lectures and the statistics tutorials will tackle the theoretical methodological aspects related the development and rational use of analytical methods in drug development which will be assessed in the first component of the summative assessment.

Summative Assessment:
The first component of assessment will be a quiz covering the topics taught during lectures and statistics tutorials (LOs 1, 2, 3, 5). The second component of assessment will be spectral/ chromatography evidence-based report (LOs 4, 2). This will require the application of your problem solving skills gained from both theoretical and experimental data interpretation sessions.

Student Activity (Notional Equivalent Study Hours (NESH))
Mode of activityLearning & Teaching ActivityNESH (Study Hours)
Face To Face Lecture 22
Face To Face Tutorial 10
Face To Face Practical classes and workshops 0
Independent Learning Guided independent study 168
Total Study Hours200
Expected Total Study Hours for Module200

Type of Assessment Weighting % LOs covered Week due Length in Hours/Words
Class Test 40 1,2,3,5 10 HOURS= 01.00
Report 60 4,2 13 , WORDS= 1000
Component 1 subtotal: 40
Component 2 subtotal: 60
Module subtotal: 100

Indicative References and Reading List - URL:
Contact your module leader