Core Module Information
Module title: Molecular Medicine

SCQF level: 10:
SCQF credit value: 20.00
ECTS credit value: 10

Module code: BMS10602
Module leader: Amy Poole
School School of Applied Sciences
Subject area group: LIFE SCIENCES
Prerequisites

Appropriate knowledge at SCQF Level 7 or 8 of Molecular Biology/Genetics

Description of module content:

Following the sequencing of the human genome, Molecular Medicine has now become a rapidly advancing field where diseases are studied at the molecular level. In this module, you will learn the advanced principles of genomics, transcriptomics and proteomics in the context of furthering our understanding of the molecular mechanisms underpinning the diagnosis and treatment of disease. You will explore the concepts of pharmacogenomics and predictive medicine and study techniques involving manipulation and measurement of DNA, RNA and proteins. You will also be introduced to in silico analysis and manipulation of RNA, DNA and protein sequence information (bioinformatics) and tutored in the use of online databases and tools for identification and comparison of DNA and protein sequences. Bioinformatics will form the basis of one of the summative assessments. Through a series of lectures and tutorials, you will study the current developments that are taking place in molecular medicine and appreciate the application of techniques to areas of interest in biomedical sciences, microbiology and biotechnology. You will also gain an understanding, from an ethical standpoint, of the implications of advanced molecular approaches such as the concept of personalised medicine and genome manipulation in embryo editing, synthetic biology and biohacking.

Learning Outcomes for module:

LO1: Demonstrate detailed knowledge and understanding of the complex features of genome organisation.
LO2: Apply knowledge of a range of ‘omics’ technologies and their applications in the field of Molecular Medicine.
LO3: Illustrate an understanding of how to interpret and discuss data from a wide range of techniques.
LO4: Employ a range of bioinformatics skills and apply in-depth knowledge to analyse genomic and proteomic sequence data.

Full Details of Teaching and Assessment
2022/3, Trimester 1, FACE-TO-FACE,
VIEW FULL DETAILS
Occurrence: 001
Primary mode of delivery: FACE-TO-FACE
Location of delivery: HONG KONG
Partner:
Member of staff responsible for delivering module: Amy Poole
Module Organiser:


Learning, Teaching and Assessment (LTA) Approach:
A bespoke, interactive core text, available on Moodle, will direct your learning of the basic principles underpinning the more advanced aspects of the topics, which will be covered in face-to-face lectures and tutorials (LOs 1, 2 and 3). Questioning and discussion are encouraged during all face-to-face teaching to promote interactive sessions. After each tutorial, online data analysis exercises and quizzes will be available on Moodle for you to reinforce your learning, gauge your own understanding and prepare you for the class test, which specifically covers interpretation and discussion of data generated by ‘omics’ technologies (LOs 2 and 3).

A dedicated face-to-face computer-based tutorial session will teach you all the necessary skills in order to complete the bioinformatics coursework assessment (LOs 1 and 4) and a final feedforward ‘skills’ session dedicated to data handling and interpretation will further prepare you for the class test.


Formative Assessment:
Face-to-face tutorials will include elements of formative assessment, including, critical thinking, problem solving, data analysis and experimental design. Online resources on Moodle will contain interactive activities such as quizzes, which provide formative feedback to enable you to gauge your progress throughout the module and reinforce your learning. You will also be provided with specialised online data analysis exercises, directly linked to the tutorial material in order to prepare you for similar style exercises in the class test.

Summative Assessment:
There are two summative assessments in this module, each with a 50% weighting. The first summative assessment is a series of online bioinformatics-based tasks to analyse genomic, transcriptomic and proteomic sequence data (LOs 1 and 4), which will form the basis of a 2000-word report for submission in week 8. The second assessment is a 2.5 hour class test (including reading time) based on molecular data analysis and interpretation (LOs 2 and 3). The class test will take place in week 13.

Student Activity (Notional Equivalent Study Hours (NESH))
Mode of activityLearning & Teaching ActivityNESH (Study Hours)
Face To Face Lecture 4
Face To Face Tutorial 10
Face To Face Practical classes and workshops 2
Independent Learning Guided independent study 181.5
Face To Face Centrally Time Tabled Examination 2.5
Total Study Hours200
Expected Total Study Hours for Module200


Assessment
Type of Assessment Weighting % LOs covered Week due Length in Hours/Words
Report 50 1 & 4 8 , WORDS= 2000
Class Test 50 2 & 3 13 HOURS= 02.50
Component 1 subtotal: 50
Component 2 subtotal: 50
Module subtotal: 100

Indicative References and Reading List - URL:
BMS10602 Molecular Medicine (Hong Kong)