Core Module Information
Module title: Current Practice in Drug Development

SCQF level: 11:
SCQF credit value: 20.00
ECTS credit value: 10

Module code: BMS11104
Module leader: David Mincher
School School of Applied Sciences
Subject area group: Life Sciences
Prerequisites

There are no pre-requisites for this module to be added

Description of module content:

You will develop a demonstrable understanding of the principles of drug development at the molecular level and the practices currently adopted in industry. You will focus on the historical origins of existing drugs and contemporary methods being used to develop new ones. You will learn to appraise and analyse physical parameters and data on drug candidate molecules. Industry-modelled case studies, individual and group activities will enhance your presentational and organizational skills to achieve competency in workshop preparation and delivery; and in writing scientific research reviews.
Origins and new sources of drugs; natural products and new pharmaceuticals; the drug discovery and development process. Molecular modelling. Stereochemistry: a source of problems in medicinal chemistry. Structure-based drug design; pharmacophore-based drug design; QSAR. Physicochemical properties and drug design: electronic factors, lipophilicity, partition coefficient, steric parameters, prediction of drug-receptor interactions, ligand binding studies. Drug formulation, prodrugs. Computational techniques: analysis of conformational space, molecular graphics and the visualisation of molecules. Molecular diversity. Combinatorial libraries and modern methods of synthesis. Current approaches to the chemotherapeutic treatment of (selected) diseases: cardiovascular disease, inflammation, cancer, viral- and bacterial- infection, diabetes, asthma, cognitive disorders. Patent application procedures and IP maintenance; legislation.

Learning Outcomes for module:

LO1: Evaluate contemporary principles and methodologies in the drug design and development process.
LO2: Appraise and analyse the physicochemical parameters underpinning drug development.
LO3: Analyse data from case studies and research publications.
LO4: Critically review the chemistry of and target validation for selected classes of leading drugs.
LO5: Appraise the implementation of patent application procedures, IP maintenance and legislation.

Full Details of Teaching and Assessment
2023/4, Trimester 1, FACE-TO-FACE, Edinburgh Napier University
VIEW FULL DETAILS
Occurrence: 001
Primary mode of delivery: FACE-TO-FACE
Location of delivery: SIGHTHILL
Partner: Edinburgh Napier University
Member of staff responsible for delivering module: David Mincher
Module Organiser:


Student Activity (Notional Equivalent Study Hours (NESH))
Mode of activityLearning & Teaching ActivityNESH (Study Hours)
Face To Face Lecture 30
Face To Face Tutorial 9
Independent Learning Guided independent study 161
Total Study Hours200
Expected Total Study Hours for Module200


Assessment
Type of Assessment Weighting % LOs covered Week due Length in Hours/Words
Report 50 1,3,4 9 HOURS= 0, WORDS= 2500
Class Test 50 1, 2, 4 & 5 13 HOURS= 2.5, WORDS= 0
Component 1 subtotal: 50
Component 2 subtotal: 50
Module subtotal: 100

Indicative References and Reading List - URL:
Contact your module leader