Module title: Toxicology and Pathology [Hong Kong]

SCQF level: 11:
SCQF credit value: 20.00
ECTS credit value: 10

Module code: BMS11605
Module leader: Sharron Vass
School School of Applied Sciences
Subject area group: Biomedical Science
Prerequisites

There are no pre-requisites for this module to be added

2019/0, Trimester 1, Blended,
Occurrence: 002
Primary mode of delivery: Blended
Location of delivery: HONG KONG
Partner:
Member of staff responsible for delivering module: Sharron Vass
Module Organiser:


Learning, Teaching and Assessment (LTA) Approach:
The module uses a student-centred approach supported by a combination of lectures and tutorials given in Hong Kong, and Moodle (LOs1-5). The case studies (1400 word limit) assess the student’s ability to critically analyse data from a variety of sources and to formulate a reasoned and holistic approach to the investigation and therapeutic approaches taken in disease management (LOs 3-5).

The majority of students taking this module will be employed in Hong Kong as laboratory scientists. Students are encouraged to bring experience from their work place to the online discussion forum. Teaching will also reflect the international nature of this programme, with a range of examples of diseases and toxicants from different parts of the world being used. Students will also use current primary reference sources throughout the module and in their assessments.
The module is supported by a VLE (Moodle) which is used to provide class materials (including lectures and tutorials/workshops), resource such as animations, videos, direct links to relevant web-based resource, e:submission of all coursework, self-assessment tests, interactive teaching resource, and independent study materials to cover expected prior-learning.




Formative Assessment:
An on-line formative self-assessment test is given early in the module. This provides an opportunity for students to get early feedback on their learning. The first case study also provides formative feedback towards the larger study.

Summative Assessment:
Case studies (week 6 & 11) requires students to answer questions based on relevant cases. The critical review (week 12) requires students to review a given set of papers. This will be set by staff in Hong Kong, based on research in their area.

Student Activity (Notional Equivalent Study Hours (NESH))
Mode of activityLearning & Teaching ActivityNESH (Study Hours)
Face To Face Lecture 15
Face To Face Tutorial 15
Independent Learning Guided independent study 170
Total Study Hours200
Expected Total Study Hours for Module200


Assessment
Type of Assessment Weighting % LOs covered Week due Length in Hours/Words
Essay 15 1 & 2 6 HOURS= 0, WORDS= 400
Report 25 3,4 & 5 11 HOURS= 0, WORDS= 1000
Report 60 1,2,3,4 & 5 12 HOURS= 0, WORDS= 2000
Component 1 subtotal: 40
Component 2 subtotal: 60
Module subtotal: 100

Description of module content:

A central theme running throughout the module will be toxicology: how xenobiotics can be causes or treatments in diseases. The basic principles of toxicokinetics (absorption, distribution, metabolism and excretion) and toxicodynamics (adverse effects in the body) will be explored in relation to named environmental pollutants, occupational hazards, and pharmaceutical agents.
The module will introduce students to the concepts of health and illness, classification of diseases, cell adaptation to disease, inflammation, cell injury/death, and neoplasia. The development of disease will be examined, together with the principles of disease pathogenesis, investigation and treatment.
Case studies of conditions such as diabetes mellitus, hepatitis, COPD and heart failure, will consolidate the related themes of the module.
This module is designed to integrate learning from the different laboratory based biomedical disciplines. Students are therefore not expected to learn medical details of all diseases, rather to gain an understanding of a range of disease processes and how these result in measurable outcomes.

Learning Outcomes for module:

Upon completion of this module you will be able to:
LO1: Critically appraise the relationship between absorption, distribution, metabolism and excretion of major drugs and toxicants
LO2: Evaluate the importance and role of dose-response relationships in toxicology and compare the actual risk of a toxicant with the perception of risk, and evaluate associated risk and hazard
LO3: Discriminate pathological processes occurring at molecular, cellular, tissue, organ and system level, including adverse effects of toxicants and ionising radiation
LO4: Critically analyse case studies integrating results of patient investigations and laboratory findings
LO5: Critically assess the investigative and therapeutic approaches applied to the diseases discussed

Indicative References and Reading List - URL:

Recommended - BOESTERLI UA (2007) MECHANISTIC TOXICOLOGY; THE MOLECULAR BASIS OF HOW CHEMICALS DISRUPT BIOLOGICAL TARGETS., 2nd ed.
Recommended - STEVENS A; LOWE J; SCOTT I (2009) CORE PATHOLOGY, 3rd ed.
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