Core Module Information
Module title: Applications of Molecular Biology

SCQF level: 10:
SCQF credit value: 20.00
ECTS credit value: 10

Module code: MIC10105
Module leader: Amy Poole
School School of Applied Sciences
Subject area group: Biomedical Science
Prerequisites

BMS09103 Molecular Genetics

Description of module content:

The module content includes; comparative analysis of eukaryotic and prokaryotic genomes, including sequencing and content of the human genome in relation to DNA profiling and predictive medicine. You will study techniques involving manipulation of DNA and RNA for analysis of gene expression including; polymerase chain reaction (PCR), quantitative (q)PCR, RNA interference (RNAi), epigenetic, microarray and in situ hybridisation studies. You will also be introduced to in silico analysis and manipulation of RNA, DNA and protein sequence information (bioinformatics) and tutored in the use of online databases and tools for identification and comparison of DNA and protein sequences. You will examine the proteome and the different techniques involved in studying protein expression such as; two-dimensional gel electrophoresis (2-DE), sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE), Western blotting and other immunological techniques.

Learning Outcomes for module:

Upon completion of this module you will be able to
LO1: Analyse and interpret features of genome organisation (both prokaryotic and eukaryotic).

LO2: Compare and contrast the properties of different sequence elements within the genome and relate these to gene expression analysis, DNA profiling and predictive medicine.

LO3: Appraise a range of ‘omics’ technologies and their applications in the analysis of genomes.
LO4: Accurately assess data from DNA sequencing, microarray, PCR, in situ hybridisation and protein analysis studies.

LO5: Employ bioinformatics skills in the analysis of genomic and proteomic sequence data.

Full Details of Teaching and Assessment

Indicative References and Reading List - URL:
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