Core Module Information
Module title: Applications of Molecular Biology [Hong Kong]

SCQF level: 10:
SCQF credit value: 20.00
ECTS credit value: 10

Module code: MIC10600
Module leader: Nicole Payton
School School of Applied Sciences
Subject area group: Biomedical Science

BMS09601 Introductory & Applied Molecular Genetics

Description of module content:

Analysis of eukaryotic and prokaryotic genome organisation. Identification/classification of repetitive DNA sequences on human genome structure and evolution. Mini-satellite DNA and short tandem repeats (STRs). DNA sequences as unique identifiers: DNA profiling in forensic science. Genomics and proteomics – technologies and application; Microarray technology and applications; Bioinformatics – use of databases and tools for comparison of DNA and protein sequences. PCR and protein engineering – PCR-based genetic engineering techniques, qualitative, semi-quantitative and quantitative PCR, real-time PCR, applications in molecular analysis. Gene cloning and expression in heterologous hosts – technology, applications, identification of potential problems associated with expressing proteins in foreign hosts. Recombinant DNA technology - cloning vectors, expression vectors, reporter systems, applications in biotechnology and medical research.

Learning Outcomes for module:

LO1: Analyse and interpret features of genome organisation.
LO2: Compare and contrast the properties, distribution and behaviour of different DNA sequence elements found in the human genome and evaluate the applications of this knowledge in biomedical and forensic laboratories.
LO3: Critically appraise PCR, and “omics” technologies and their applications in the analysis of genomes and gene expression.
LO4: Analyse and interpret data from DNA sequencing, microarrays and PCR analysis.
LO5: Compare and contrast strategies for gene cloning and genetic engineering, including heterologous gene expression.

Full Details of Teaching and Assessment
2020/1, Trimester 1, BLENDED,
Occurrence: 001
Primary mode of delivery: BLENDED
Location of delivery: HONG KONG
Member of staff responsible for delivering module: Nicole Payton
Module Organiser:

Learning, Teaching and Assessment (LTA) Approach:
Learning & teaching methods including their alignment to LOs
Introductory Lectures and tutorial sessions together with study material provided by webCT will cover LOs1-5. This will be supported by face-to-face lectures and tutorials delivered by local tutors, during which students work in small groups to undertake exercises in experiment design, problem-solving or critiquing a paper. Questioning is encouraged during face-to-face teaching in both lectures and tutorials, and on-line using the discussion boards. Elements of LO4 are covered by a combination of on-line learning and a coursework assignment. Personalised feedback is given on the coursework component (bioinformatics report).

Formative Assessment:
Tutorials will include elements of formative assessment.

Summative Assessment:
Summative assessment takes the form of coursework (LO4) and a formal examination (LOs 1 - 5). A 3 hour examination is required to allow students to complete data analysis/interpretation questions.

Student Activity (Notional Equivalent Study Hours (NESH))
Mode of activityLearning & Teaching ActivityNESH (Study Hours)
Independent Learning Guided independent study 121
Face To Face Centrally Time Tabled Examination 3
Face To Face Lecture 4
Face To Face Tutorial 12
Online Guided independent study 60
Total Study Hours200
Expected Total Study Hours for Module200

Type of Assessment Weighting % LOs covered Week due Length in Hours/Words
Centrally Time Tabled Examination 60 1,2,3,4,5 14/15 HOURS= 3, WORDS= 0
Report 40 4 10 HOURS= 0, WORDS= 1000
Component 1 subtotal: 40
Component 2 subtotal: 60
Module subtotal: 100

Indicative References and Reading List - URL:
Contact your module leader