To study this module you will need the learning equivalent to the module listed below or have passed this module:

BMS09803 Molecular Genetics [Sri Lanka]

Analysis of eukaryotic and prokaryotic genome organisation. Identification/classification of repetitive DNA sequences on human genome structure and evolution. Mini-satellite DNA and short tandem repeats (STRs). DNA sequences as unique identifiers: DNA profiling in forensic science. Genomics and proteomics – technologies and application; Microarray technology and applications; Bioinformatics – use of databases and tools for comparison of DNA and protein sequences. PCR and protein engineering – PCR-based genetic engineering techniques, qualitative, semi-quantitative and quantitative PCR, real-time PCR, applications in molecular analysis. Gene cloning and expression in heterologous hosts – technology, applications, identification of potential problems associated with expressing proteins in foreign hosts. Recombinant DNA technology - cloning vectors, expression vectors, reporter systems, applications in biotechnology and medical research.

Upon completion of this module you will be able to:
LO1: Analyse and interpret features of genome organisation.
LO2: Compare and contrast the properties, distribution and behaviour of different DNA sequence elements found in the human genome and evaluate the applications of this knowledge in biomedical and forensic laboratories.
LO3: Critically appraise PCR, and “omics” technologies and their applications in the analysis of genomes and gene expression.
LO4: Analyse and interpret data from DNA sequencing, microarrays and PCR analysis.
LO5: Compare and contrast strategies for gene cloning and genetic engineering, including heterologous gene expression.