Modules

Module title: Molecular Pathogenesis of Microbial Infection
SCQF level: 11:
SCQF credit value: 20.00
ECTS credit value: 10
Module code: MIC11100
Module leader: Clare Taylor
School School of Applied Sciences
Subject area group: Microbiology & Drug Discovery
Prerequisites

There are no pre-requisites for this module to be added
2018/9, Trimester 2, Face-to-Face, Edinburgh Napier University
Occurrence: 001
Primary mode of delivery: Face-to-Face
Location of delivery: SIGHTHILL
Partner: Edinburgh Napier University
Member of staff responsible for delivering module: Clare Taylor
Module Organiser:


Learning, Teaching and Assessment (LTA) Approach:
This module will be delivered through a combination of face-to-face lectures, tutorials (LO1–3) and laboratory sessions (LO4). Teaching approaches will include group work in the form of problem-based learning exercises and critique of literature (LO1-6).
Key employability skills for scientists are embedded throughout the module including laboratory skills, evaluating experimental data, problem-solving, critical appraisal of literature and scientific writing.
Recent developments in the understanding of microbial pathogenesis will be emphasised using peer-reviewed scientific literature. Where appropriate, exemplars of research will be used to illustrate examples. Laboratory classes will be used to deliver research-based themes.
The themes covered in this module will cover pathogens of global importance and examples will be drawn from international research published in international journals.
The module is supported by a VLE (Moodle) which is used to provide class materials (including lectures, tutorials and laboratory classes), resource such as animations, videos, direct links to relevant web-based resource, e:submission of all coursework, self-assessment test, interactive teaching resource, and independent study materials to cover expected prior-learning. Reflecting the discipline, students use a wide range of technology to accomplish laboratory work and in silico analysis.
Formative Assessment:
Compulsory formative assessment will be a mock exam; peer feedback will be discussed in class time
The discursive nature of this module will provide many opportunities for formative feedforward and feedback around learning and assessment, most particularly on a continuous basis within laboratory sessions. A workshop on critical analysis of original research articles, reading and writing early in the module will help support students in remaining discussions and in preparing for their oral assessment, and the final exam. A formative mock exam held later in the module will support the students in their summative exam and provide an important feedback and feedforward opportunity.



Summative Assessment:
Summative assessment will be in the form of an examination which will be used to assess understanding of key aspects of the module (LO1,3-4).
Coursework, which will be supported through interactive class activities, will provide both formative and summative assessment (LO2).
Student Activity (Notional Equivalent Study Hours (NESH))
Mode of activityLearning & Teaching ActivityNESH (Study Hours)
Face To Face Lecture 22
Face To Face Tutorial 11
Face To Face Practical classes and workshops 12
Independent Learning Guided independent study 153
Face To Face Centrally Time Tabled Examination 2
Total Study Hours200
Expected Total Study Hours for Module200


Assessment
Type of Assessment Weighting % LOs covered Week due Length in Hours/Words
Oral Presentation 50 2 8 HOURS= 0.15, WORDS= 0
Centrally Time Tabled Examination 50 1,3 & 4 13 HOURS= 2, WORDS= 0
Component 1 subtotal: 50
Component 2 subtotal: 50
Module subtotal: 100

Description of module content:

In this module you will examine the molecular themes underpinning the pathogenesis of microbial infection. You will examine the responses of microbes to external stimuli and understand the molecular mechanisms that modulate genetic regulation of virulence factors and microbial stress responses that ensure survival and infection in the host. The host response to microbial infection: innate and acquired immune response to infection; Invasion & colonisation of the host: molecular mechanisms of pathogenesis; Virulence factors involved in adhesion, invasion and colonisation; molecular structure and genetic regulation. Overcoming antimicrobial resistance: antibiotics/antivirals/antifungals and resistance; bacterial physiology and novel therapeutics.
Learning Outcomes for module:

LO1: Analyse the dynamic interactions that take place between host and microbe during the establishment of infection.
LO2: Examine the impact of antimicrobial resistance as a driver for development of novel antimicrobial therapeutics.
LO3: Critically review and challenge scientific literature to develop analytical and communication skills.
LO4: Select and apply appropriate laboratory techniques to enhance understanding of key knowledge that underpins the module learning outcomes.

Indicative References and Reading List - URL:

Recommended - CELLULAR MICROBIOLOGY: WILEY BLACKWELL
Recommended - MOLECULAR MICROBIOLOGY: WILEY BLACKWELL
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